Long-Acting MOUD focuses on extended-release buprenorphine and naltrexone formulations that remove daily dosing barriers, stabilize serum levels, and improve retention in opioid use disorder. This page turns pharmacology into operations your team can run now: candidacy screening (readiness, goals, and prior MOUD history), induction choices (traditional, micro-induction, or post-detox), and clinic flow that makes the first injection or implant happen the same day motivation appears. We map consent, pregnancy and lactation considerations, hepatic/renal checks, and coordination with pain care so patients don’t get bounced when procedures or acute injuries occur. If you’re comparing options at a long-acting MOUD conference, you’ll find scripts for stigma-free conversations, checklists for dose timing, and pathways for transitions between oral and long-acting forms without withdrawal. Because sleep, stress, and social friction drive relapse, we pair medication with circadian anchors, brief CBT/MI, contingency management, and peer navigation that solves practical problems like transport, IDs, and benefits.

Implementation lives in details—stock, storage, scheduling, and follow-through. We outline pharmacy partnerships, cold-chain and inventory rules, billing codes, and injection-room choreography that respects privacy and speed. Missed-dose recovery plans cover grace windows, bridging with sublingual doses, and post-incarceration re-starts. Equity features—interpreters, low-literacy materials with visuals, evening/weekend hours, and mobile teams—turn interest into continuity, especially for people juggling shift work, caregiving, or homelessness. Pain and perioperative care need clear guidance: communicate with surgeons/EDs about continuing buprenorphine, non-opioid adjuncts, and split dosing during severe pain. We include perinatal pathways that prioritize maternal stabilization, neonatal safety, and non-punitive social supports. Dashboards track coverage (starts per 1,000 patients), retention, overdoses, and quality of life; case huddles fix leaks fast. When clinics engineer reliability around long-acting choices, patients get breathing room to rebuild sleep, work, and relationships—and communities see fewer funerals.