Fentanyl and Overdose Science
Fentanyl and Overdose Science synthesizes what teams must know to prevent deaths in a highly potent, rapidly shifting drug supply. This page turns evidence into practice: naloxone distribution and training; high-coverage MOUD strategies; xylazine and polysubstance risk management; and data systems that detect clusters early. If you’re evaluating an overdose prevention conference, you’ll find protocols for post-overdose outreach, ED-initiated buprenorphine, wound care, and drug-checking partnerships. Because stigma kills, messaging centers on dignity, safety, and practical steps that keep people alive long enough to benefit from treatment.
We outline neighborhood-level alerting, pharmacy collaborations, and mobile that bring supplies and care to hotspots. Programs use escalating coverage metrics—MOUD starts, naloxone kits per 1,000 residents, test strip dteams istribution—to guide budgets. Post-overdose, warm handoffs and peer navigation reduce repeat events; families get training and rescue kits. Equity and language access are built in; data governance protects privacy. For hospital-based linkage and step-down models, see Consultation-Liaison and SUD.
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Naloxone at scale
- Normalize carry and use; train peers, families, and staff.
- Track distribution and reversals to target gaps.
MOUD everywhere
- ED, inpatient, and primary care starts with same-day pharmacy.
- Reduce prior auths and cost barriers; offer long-acting options.
Drug checking and signals
- Partner with labs and community sites; share credible alerts.
- Watch for xylazine and benzodiazepine co-exposures.
Post-overdose pathways
- Bedside outreach and 72-hour follow-ups with peers.
- Safety planning and harm-reduction supplies on discharge.
Field Operations, Equity, and Measurement
Mobile and fixed sites
Supply hubs with wound care, safer-use kits, and tele-MOUD.
Family/caregiver training
Simple scripts and practice; address fear and legal myths.
Justice interfaces
Bridge scripts pre-release; avoid forced withdrawal.
Rural adaptations
Mail-based kits, tele-supports, and pharmacy partners.
Data governance
De-identified dashboards and clear consent language.
Funding alignment
Tie budgets to coverage and outcome metrics.
Public communication
Plain-language campaigns with local partners.
Continuous learning
Iterate based on reversals, deaths, and linkage rates.
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