Cognitive Dysfunction in Severe Mental Illness

Cognitive Dysfunction in Severe Mental Illness addresses attention, processing speed, memory, and executive deficits that drive disability in schizophrenia spectrum, bipolar disorder, and recurrent depression. This page makes cognition visible in clinic: brief assessments you can run, how to set functional goals around learning and work, and which treatments actually move the needle—CBT-informed compensatory strategies, cognitive remediation, exercise and sleep plans, and medication choices that minimize cognitive drag. For attendees comparing an SMI cognition conference, we outline team-based pathways that blend skills training, digital supports, and role recovery.

Function is the outcome that matters. We connect cognitive profiles to practical scaffolds—checklists, chunking, external memory aids, and environmental modifications—and show how to build “friction” against distractors while increasing cues for desired routines. Medications are reviewed for anticholinergic burden and sedation; long-acting formulations can stabilize adherence. Fitness, daylight, and sleep regularity boost cognitive efficiency. When psychosis or mood instability is active, stabilization precedes intensive training; once steady, remediation and work/school reintegration sustain gains. See Cognitive Remediation for protocol detail that complements this page’s systems view.

What to Measure, What to Do

Brief cognitive assessment

  • Use validated screeners and functional tasks to profile deficits.
  • Tie results to work/school and daily-living targets.

Compensatory skills and environment

  • Externalize memory and sequence tasks; reduce distractors.
  • Build routines with visual cues and time-blocking.

Medication and physiology

  • Lower anticholinergic load; avoid sedative overhang.
  • Stabilize sleep, light exposure, and activity for cognitive gain.

Role recovery plans

  • Grade return to school/work; align supports and expectations.
  • Use peer coaching to sustain practice between visits.

Programs, Tools, and Equity

Cognitive remediation access
Offer group/individual formats; combine drill-and-strategy work.

Digital coaching
Apps for reminders, sequencing, and progress tracking.

Integrated care teams
Therapists, prescribers, OTs, and vocational specialists align.

Measurement and QI
Track function and participation, not just test scores.

Youth and early psychosis
Intervene early; link to education supports and families.

Late-life SMI
Account for medical comorbidity and sensory deficits.

Equity and literacy
Use plain language and low-tech options when needed.

Sustainability
Create home practice plans and booster sessions.

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